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Zika virus vertical transmission research

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In this Outbreak NewsBites podcast, I look briefly at new research from the University of South Florida (USF) on Zika virus vertical transmission. See the paper here: Zika Virus–Infected Decidual Cells...

Zika: Research team use experimental drug that reduces replication of the virus and prevents microcephaly in mice

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An international group of researchers have discovered that inhibiting AHR (aryl hydrocarbon receptor), a protein with roles in regulating immunity, stem cell maintenance and cellular differentiation, enables...

Why Zika virus caused most harmful brain damage to Brazilian newborns

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Due to Zika virus, more than 1,600 babies were born in Brazil with microcephaly, or abnormally small heads, from September 2015 through April 2016. The epidemic took health professionals by surprise because...

The Top Infectious Disease Stories of the Decade 2010-2019: The Podcast

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In this podcast, I look at what I believe are the top infectious disease stories of the last decade.   Related: Texas anthrax: A look at the 2019 outbreak Naegleria fowleri: The PAM protocol with...

How in utero Zika virus infection can lead to microcephaly in newborns: Baylor research

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A new study led by researchers at Baylor College of Medicine revealed how in utero Zika virus infection can lead to microcephaly in newborns. The team discovered that the Zika virus protein NS4A disrupts...

Zika brain damage may go undetected in pregnancy

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Zika virus may cause significant damage to the fetal brain even when the baby’s head size is normal, according to a new animal study led by researchers at the University of Washington School of Medicine...

More birth defects seen in parts of U.S. with local Zika spread: CDC

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Birth defects most strongly linked to Zika virus infection during pregnancy have increased in parts of the United States that have had local Zika virus transmission, according to a report in CDC’s Morbidity...

Zika’s mechanism for inducing congenital microcephaly

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Epidemiological studies show that in utero fetal infection with the Zika virus (ZIKV) may lead to microcephaly, an irreversible congenital malformation of the brain characterized by an incomplete development...

Brazil Zika outbreak: ‘May be coming to an end’

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In 2016, news about the Zika virus in Brazil made the headlines in Europe for the first time. With approximately 65 million people affected, it is one of the largest epidemics in the last few years. The...

Hydroxychloroquine, a malaria drug, protects fetal mice from Zika virus: Study finds

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Hydroxychloroquine, a drug approved by the Food and Drug Administration to treat malaria and certain autoimmune diseases in pregnant women, appears to reduce transmission of Zika virus from pregnant mice...